In the period at the end of XIX and the beginning of the XX century, the region of Southeast Europe was swirling in intensive political and social and economic changes. Some of these changes started to awaken the entrepreneurship spirit of individuals and distinguished families in the Tikvesh wine region, who saw the potential for development and commerce it offered, and they started to establish wineries producing quality wines in bottles clearly labeling the geographic origin of the wine. This was the first time the centuries long tradition was given a name which generically connected with the region of origin, i.e… “Tikvesh”. The first time “Tikvesh” was mentioned in a written document was exactly in this period, to be more exact, the year 1885, which is considered the year when organized production and sales of wine first started in Macedonia.